HMS Anson was a 64-gun third rate ship of the line of the Royal Navy, launched at Plymouth on 4 September 1781 by Georgina, Duchess of Devonshire. She fought at the Battle of Les Saintes on 9 April 1782 under the flag of Admiral Sir George Rodney against Admiral de Grasse. In this engagement, Captain William Blair was one of the two Royal Navy post captains killed. In 1794, she was razeed to a large frigate of 44-guns by removing her forecastle and quarterdeck and altering the former upper deck (now weather or spar-deck) to 42-pounder carronades from the 18-pounder long guns previously mounted.

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